Co-opted JNK/SAPK Signaling in Wnt/β-catenin–Induced Tumorigenesis
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چکیده
منابع مشابه
Co-opted JNK/SAPK Signaling in Wnt/β-catenin–Induced Tumorigenesis
Aberrant stimulation of the canonical Wnt pathway induces mammary tumorigenesis in mice. It has been well documented that two types of tumors, adenocarcinoma and adenocarcinoma with squamous metaplasia, develop in these mutants. However, the molecular mechanism underlying the induction of squamous transdifferentiation remains largely unknown. Here, we show that JNK/SAPK signaling plays an impor...
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ژورنال
عنوان ژورنال: Neoplasia
سال: 2008
ISSN: 1476-5586
DOI: 10.1593/neo.08548